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Design and Validation of a Human Brain Endothelial Microvessel-on-a-Chip Open Microfluidic Model Enabling Advanced Optical Imaging
We describe here the design and implementation of an in vitro microvascular open model system using human brain microvascular endothelial cells. The design has several advantages over other traditional closed microfluidic platforms: (1) it enables controlled unidirectional flow of media at physiolog...
Autores principales: | Salman, Mootaz M., Marsh, Graham, Kusters, Ilja, Delincé, Matthieu, Di Caprio, Giuseppe, Upadhyayula, Srigokul, de Nola, Giovanni, Hunt, Ronan, Ohashi, Kazuka G., Gray, Taylor, Shimizu, Fumitaka, Sano, Yasuteru, Kanda, Takashi, Obermeier, Birgit, Kirchhausen, Tom |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576009/ https://www.ncbi.nlm.nih.gov/pubmed/33117784 http://dx.doi.org/10.3389/fbioe.2020.573775 |
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