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Crocin induces autophagic cell death and inhibits cell invasion of cervical cancer SiHa cells through activation of PI3K/AKT

BACKGROUND: Cervical cancer is a prevalent tumor mainly induced by Human Papilloma Virus (HPV). Autophagy was inactivated with HPV to promote cancer progression. Here we explored the effects of crocin on cervical cancer cells, mainly on autophagy and apoptosis. METHODS: SiHa cells were treated with...

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Detalles Bibliográficos
Autores principales: Zhang, Jian, Yang, Shaoping, Wang, Kana, Huang, Yu, Yang, Nian, Yang, Zhongmei, Zheng, Zhenrong, Wang, Yujue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576020/
https://www.ncbi.nlm.nih.gov/pubmed/33241029
http://dx.doi.org/10.21037/atm-20-5882