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Ulinastatin alleviates cerebral ischemia-reperfusion injury in rats by activating the Nrf-2/HO-1 signaling pathway

BACKGROUND: Ulinastatin, a urinary trypsin inhibitor, is one of the widely used auxiliary drugs in the rescue of acute circulatory failure. This study aims to explore the protective mechanisms of ulinastatin on cerebral ischemia-reperfusion (I/R) injury. METHODS: A cerebral MCAO was established with...

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Detalles Bibliográficos
Autores principales: Cui, Lei, Cao, Wei, Xia, Yanmin, Li, Xiaofang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576027/
https://www.ncbi.nlm.nih.gov/pubmed/33240985
http://dx.doi.org/10.21037/atm-20-5115