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Ligustilide alleviates podocyte injury via suppressing the SIRT1/NF-κB signaling pathways in rats with diabetic nephropathy

BACKGROUND: Diabetic nephropathy (DN) is one of the common chronic microvascular complications of diabetes, and podocyte injury and dysfunction are strictly related to the pathogenesis of DN. Studies have shown that ligustilide (LIG) has anti-inflammatory, antioxidant, and anti-apoptotic activities....

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Detalles Bibliográficos
Autores principales: Xu, Feng, Ye, Zi, Tao, Shuo, Liu, Wangshu, Su, Jianbing, Fang, Xingxing, Wang, Xueqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576076/
https://www.ncbi.nlm.nih.gov/pubmed/33241003
http://dx.doi.org/10.21037/atm-20-5811