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Expression of SARS-CoV-2 entry factors in lung epithelial stem cells and its potential implications for COVID-19

SARS-CoV-2 can infiltrate the lower respiratory tract, resulting in severe respiratory failure and a high death rate. Normally, the airway and alveolar epithelium can be rapidly reconstituted by multipotent stem cells after episodes of infection. Here, we analyzed published RNA-seq datasets and demo...

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Detalles Bibliográficos
Autores principales: Valyaeva, Anna A., Zharikova, Anastasia A., Kasianov, Artem S., Vassetzky, Yegor S., Sheval, Eugene V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576138/
https://www.ncbi.nlm.nih.gov/pubmed/33082395
http://dx.doi.org/10.1038/s41598-020-74598-5