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Novel and potent antimicrobial effects of caspofungin on drug-resistant Candida and bacteria

Echinocandins, including caspofungin, micafungin, and anidulafungin, are first-line antifungal agents for the treatment of invasive candidiasis. They exhibit fungicidal activity by inhibiting the synthesis of β-1,3-d-glucan, an essential component of the fungal cell wall. However, they are active on...

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Detalles Bibliográficos
Autores principales: Sumiyoshi, Makoto, Miyazaki, Taiga, Makau, Juliann Nzembi, Mizuta, Satoshi, Tanaka, Yoshimasa, Ishikawa, Takeshi, Makimura, Koichi, Hirayama, Tatsuro, Takazono, Takahiro, Saijo, Tomomi, Yamaguchi, Hiroyuki, Shimamura, Shintaro, Yamamoto, Kazuko, Imamura, Yoshifumi, Sakamoto, Noriho, Obase, Yasushi, Izumikawa, Koichi, Yanagihara, Katsunori, Kohno, Shigeru, Mukae, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576149/
https://www.ncbi.nlm.nih.gov/pubmed/33082485
http://dx.doi.org/10.1038/s41598-020-74749-8