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Neonatal monocytes demonstrate impaired homeostatic extravasation into a microphysiological human vascular model

Infections are most frequent at the extremes of life, especially among newborns, reflecting age-specific differences in immunity. Monocytes maintain tissue-homeostasis and defence-readiness by escaping circulation in the absence of inflammation to become tissue-resident antigen presenting cells in v...

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Detalles Bibliográficos
Autores principales: Sanchez-Schmitz, Guzman, Morrocchi, Elena, Cooney, Mitchell, Soni, Dheeraj, Khatun, Rahima, Palma, Paolo, Dowling, David J., Levy, Ofer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576166/
https://www.ncbi.nlm.nih.gov/pubmed/33082466
http://dx.doi.org/10.1038/s41598-020-74639-z