Siah2 integrates mitogenic and extracellular matrix signals linking neuronal progenitor ciliogenesis with germinal zone occupancy

Evidence is lacking as to how developing neurons integrate mitogenic signals with microenvironment cues to control proliferation and differentiation. We determine that the Siah2 E3 ubiquitin ligase functions in a coincidence detection circuit linking responses to the Shh mitogen and the extracellula...

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Detalles Bibliográficos
Autores principales: Ong, Taren, Trivedi, Niraj, Wakefield, Randall, Frase, Sharon, Solecki, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576183/
https://www.ncbi.nlm.nih.gov/pubmed/33082319
http://dx.doi.org/10.1038/s41467-020-19063-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576183/
https://www.ncbi.nlm.nih.gov/pubmed/33082319
http://dx.doi.org/10.1038/s41467-020-19063-7

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