Telomere damage induces internal loops that generate telomeric circles

Extrachromosomal telomeric circles are commonly invoked as important players in telomere maintenance, but their origin has remained elusive. Using electron microscopy analysis on purified telomeres we show that, apart from known structures, telomeric repeats accumulate internal loops (i-loops) that...

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Detalles Bibliográficos
Autores principales: Mazzucco, Giulia, Huda, Armela, Galli, Martina, Piccini, Daniele, Giannattasio, Michele, Pessina, Fabio, Doksani, Ylli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576219/
https://www.ncbi.nlm.nih.gov/pubmed/33082350
http://dx.doi.org/10.1038/s41467-020-19139-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576219/
https://www.ncbi.nlm.nih.gov/pubmed/33082350
http://dx.doi.org/10.1038/s41467-020-19139-4

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