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Calycosin inhibited autophagy and oxidative stress in chronic kidney disease skeletal muscle atrophy by regulating AMPK/SKP2/CARM1 signalling pathway

Skeletal muscle atrophy is a common and serious complication of chronic kidney disease (CKD). Oxidative stress and autophagy are the primary molecular mechanisms involved in muscle atrophy. Calycosin, a major component of Radix astragali, exerts anti‐inflammatory, anti‐oxidative stress and anti‐auto...

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Detalles Bibliográficos
Autores principales: Hu, Rong, Wang, Ming‐qing, Liu, Ling‐yu, You, Hai‐yan, Wu, Xiao‐hui, Liu, Yang‐yang, Wang, Yan‐jing, Lu, Lu, Xiao, Wei, Wei, Lian‐bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576237/
https://www.ncbi.nlm.nih.gov/pubmed/32910538
http://dx.doi.org/10.1111/jcmm.15514