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Metabolic dysfunction in human skin: Restoration of mitochondrial integrity and metabolic output by nicotinamide (niacinamide) in primary dermal fibroblasts from older aged donors

Alterations in metabolism in skin are accelerated by environmental stressors such as solar radiation, leading to premature aging. The impact of aging on mitochondria is of interest given their critical role for metabolic output and the finding that environmental stressors cause lowered energy output...

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Detalles Bibliográficos
Autores principales: Oblong, John E., Bowman, Amy, Rovito, Holly A., Jarrold, Bradley B., Sherrill, Joseph D., Black, Markaisa R., Nelson, Glyn, Kimball, Alexa B., Birch‐Machin, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576238/
https://www.ncbi.nlm.nih.gov/pubmed/32990346
http://dx.doi.org/10.1111/acel.13248