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Metabolic dysfunction in human skin: Restoration of mitochondrial integrity and metabolic output by nicotinamide (niacinamide) in primary dermal fibroblasts from older aged donors
Alterations in metabolism in skin are accelerated by environmental stressors such as solar radiation, leading to premature aging. The impact of aging on mitochondria is of interest given their critical role for metabolic output and the finding that environmental stressors cause lowered energy output...
Autores principales: | Oblong, John E., Bowman, Amy, Rovito, Holly A., Jarrold, Bradley B., Sherrill, Joseph D., Black, Markaisa R., Nelson, Glyn, Kimball, Alexa B., Birch‐Machin, Mark A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576238/ https://www.ncbi.nlm.nih.gov/pubmed/32990346 http://dx.doi.org/10.1111/acel.13248 |
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