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Aging‐induced aberrant RAGE/PPARα axis promotes hepatic steatosis via dysfunctional mitochondrial β oxidation

Non‐alcoholic fatty liver disease (NAFLD), characterized by an increase in hepatic triglyceride (TG) content, is the most common liver disease worldwide. Aging has been shown to increase susceptibility to NAFLD; however, the underlying molecular mechanism remains poorly understood. In the present st...

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Detalles Bibliográficos
Autores principales: Wan, Jian, Wu, Xiangsong, Chen, Hanbei, Xia, Xinyi, Song, Xi, Chen, Song, Lu, Xinyuan, Jin, Jie, Su, Qing, Cai, Dongsheng, Liu, Bin, Li, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576254/
https://www.ncbi.nlm.nih.gov/pubmed/32936538
http://dx.doi.org/10.1111/acel.13238