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METTL3 potentiates resistance to cisplatin through m(6)A modification of TFAP2C in seminoma

Testicular germ cell tumours (TGCTs) rank as the most common malignancy in men aged 20‐34 years, and seminomas are the most type of TGCTs. As a crucial anti‐tumour agent with explicit toxicity, cisplatin may render resistance through intertwined mechanisms, even in disease entities with high curativ...

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Detalles Bibliográficos
Autores principales: Wei, Jingchao, Yin, Yinghao, Zhou, Jun, Chen, Hanfei, Peng, Jingxuan, Yang, Jianfu, Tang, Yuxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576266/
https://www.ncbi.nlm.nih.gov/pubmed/32857912
http://dx.doi.org/10.1111/jcmm.15738