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Age‐related differences in the translational landscape of mammalian oocytes

Increasing maternal age in mammals is associated with poorer oocyte quality, involving higher aneuploidy rates and decreased developmental competence. Prior to resumption of meiosis, fully developed mammalian oocytes become transcriptionally silent until the onset of zygotic genome activation. There...

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Detalles Bibliográficos
Autores principales: del Llano, Edgar, Masek, Tomas, Gahurova, Lenka, Pospisek, Martin, Koncicka, Marketa, Jindrova, Anna, Jansova, Denisa, Iyyappan, Rajan, Roucova, Kristina, Bruce, Alexander W., Kubelka, Michal, Susor, Andrej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576272/
https://www.ncbi.nlm.nih.gov/pubmed/32951297
http://dx.doi.org/10.1111/acel.13231