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The neurofibromatosis type I gene promotes autophagy via mTORC1 signalling pathway to enhance new bone formation after fracture

Bone fracture is one of the most common injuries. Despite the high regenerative capacity of bones, failure of healing still occurs to near 10% of the patients. Herein, we aim to investigate the modulatory role of neurofibromatosis type I gene (NF1) to osteogenic differentiation of bone marrow–derive...

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Detalles Bibliográficos
Autores principales: Tan, Qian, Wu, Jiang‐Yan, Liu, Yao‐Xi, Liu, Kun, Tang, Jin, Ye, Wei‐Hua, Zhu, Guang‐Hui, Mei, Hai‐Bo, Yang, Ge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576311/
https://www.ncbi.nlm.nih.gov/pubmed/32862562
http://dx.doi.org/10.1111/jcmm.15767