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Regulatory T cells for minimising immune suppression in kidney transplantation: phase I/IIa clinical trial

OBJECTIVE: To assess whether reshaping of the immune balance by infusion of autologous natural regulatory T cells (nTregs) in patients after kidney transplantation is safe, feasible, and enables the tapering of lifelong high dose immunosuppression, with its limited efficacy, adverse effects, and hig...

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Detalles Bibliográficos
Autores principales: Roemhild, Andy, Otto, Natalie Maureen, Moll, Guido, Abou-El-Enein, Mohamed, Kaiser, Daniel, Bold, Gantuja, Schachtner, Thomas, Choi, Mira, Oellinger, Robert, Landwehr-Kenzel, Sybille, Juerchott, Karsten, Sawitzki, Birgit, Giesler, Cordula, Sefrin, Anett, Beier, Carola, Wagner, Dimitrios Laurin, Schlickeiser, Stephan, Streitz, Mathias, Schmueck-Henneresse, Michael, Amini, Leila, Stervbo, Ulrik, Babel, Nina, Volk, Hans-Dieter, Reinke, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576328/
https://www.ncbi.nlm.nih.gov/pubmed/33087345
http://dx.doi.org/10.1136/bmj.m3734