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Targeting interleukin-17 receptor B enhances gemcitabine sensitivity through downregulation of mucins in pancreatic cancer

Pancreatic cancer is the fourth leading cause of death worldwide due to its poorest prognoses with a 7% 5-year survival rate. Eighty percent of pancreatic cancer patients relapse after chemotherapy and develop early metastasis and drug resistance. Resistance to nucleoside analog gemcitabine frequent...

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Detalles Bibliográficos
Autores principales: Tsai, Lung-Hung, Hsu, Kai-Wen, Chiang, Cheng-Ming, Yang, Hsiu-Ju, Liu, Yu-Huei, Yang, Shun-Fa, Peng, Pei-Hua, Cheng, Wei-Chung, Wu, Heng-Hsiung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576602/
https://www.ncbi.nlm.nih.gov/pubmed/33082357
http://dx.doi.org/10.1038/s41598-020-73659-z