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The hepatic lipidome and HNF4α and SHBG expression in human liver

Low plasma levels of sex hormone-binding globulin (SHBG) are a marker for obesity, insulin resistance, non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes. The transcription factor HNF4α is a major determinant of hepatic SHBG expression and thereby serum SHBG levels, and mediates in part t...

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Detalles Bibliográficos
Autores principales: Winters, Stephen J, Scoggins, Charles R, Appiah, Duke, Ghooray, Dushan T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576643/
https://www.ncbi.nlm.nih.gov/pubmed/33064664
http://dx.doi.org/10.1530/EC-20-0401