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Resveratrol mediates mechanical allodynia through modulating inflammatory response via the TREM2-autophagy axis in SNI rat model

BACKGROUND: Neuropathic pain (NeuP) is a chronic and challenging clinical problem, with little effective treatment. Resveratrol has shown neuroprotection by inhibiting inflammatory response in NeuP. Recently, the triggering receptor expressed on myeloid cells 2 (TREM2) expressed by microglia was ide...

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Detalles Bibliográficos
Autores principales: Wang, Yaping, Shi, Yu, Huang, Yongquan, Liu, Wei, Cai, Guiyuan, Huang, Shimin, Zeng, Yanyan, Ren, Siqiang, Zhan, Hongrui, Wu, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576710/
https://www.ncbi.nlm.nih.gov/pubmed/33081801
http://dx.doi.org/10.1186/s12974-020-01991-2