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Resveratrol mediates mechanical allodynia through modulating inflammatory response via the TREM2-autophagy axis in SNI rat model
BACKGROUND: Neuropathic pain (NeuP) is a chronic and challenging clinical problem, with little effective treatment. Resveratrol has shown neuroprotection by inhibiting inflammatory response in NeuP. Recently, the triggering receptor expressed on myeloid cells 2 (TREM2) expressed by microglia was ide...
Autores principales: | Wang, Yaping, Shi, Yu, Huang, Yongquan, Liu, Wei, Cai, Guiyuan, Huang, Shimin, Zeng, Yanyan, Ren, Siqiang, Zhan, Hongrui, Wu, Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576710/ https://www.ncbi.nlm.nih.gov/pubmed/33081801 http://dx.doi.org/10.1186/s12974-020-01991-2 |
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