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Activation of the KDM5A/miRNA-495/YTHDF2/m6A-MOB3B axis facilitates prostate cancer progression

BACKGROUND: Accumulating evidence supports that lysine-specific demethylase 5 (KDM5) family members act as oncogenic drivers. This study was performed to elucidate the potential effects of KDM5A on prostate cancer (PCa) progression via the miR-495/YTHDF2/m6A-MOB3B axis. METHODS: The expression of KD...

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Detalles Bibliográficos
Autores principales: Du, Chen, Lv, Caihong, Feng, Yue, Yu, Siwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576758/
https://www.ncbi.nlm.nih.gov/pubmed/33087165
http://dx.doi.org/10.1186/s13046-020-01735-3