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Valproic acid inhibits interferon-γ production by NK cells and increases susceptibility to Listeria monocytogenes infection

Valproic acid (VPA) is a drug commonly used for epileptic seizure control. Recently, it has been shown that VPA alters the activation of several immune cells, including Natural Killer (NK) cells, which play an important role in the containment of viruses and intracellular bacteria. Although VPA can...

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Detalles Bibliográficos
Autores principales: Soria-Castro, Rodolfo, Chávez-Blanco, Alma D., García-Pérez, Blanca Estela, Wong-Baeza, Isabel, Flores-Mejía, Raúl, Flores-Borja, Fabián, Estrada-Parra, Sergio, Estrada-García, Iris, Serafín-López, Jeanet, Chacón-Salinas, Rommel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576816/
https://www.ncbi.nlm.nih.gov/pubmed/33082490
http://dx.doi.org/10.1038/s41598-020-74836-w