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Antiparasitic Behavior of Trifluoromethylated Pyrazole 2-Amino-1,3,4-thiadiazole Hybrids and Their Analogues: Synthesis and Structure-Activity Relationship

A series of trifluoromethylated pyrazole thiosemicarbazone, trifluromethylated pyrazole isothiosemicarbazone, and trifluoromethylated pyrazole 2-amino-1,3,4-thiadiazole hybrids were synthesized and evaluated in vitro against the promastigote form of Leishmania amazonensis and the epimastigote form o...

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Detalles Bibliográficos
Autores principales: Camargo, Jeniffer do Nascimento Ascencio, Pianoski, Karlos Eduardo, dos Santos, Mariellen Guilherme, Lazarin-Bidóia, Danielle, Volpato, Hélito, Moura, Sidnei, Nakamura, Celso Vataru, Rosa, Fernanda Andreia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576996/
https://www.ncbi.nlm.nih.gov/pubmed/33117181
http://dx.doi.org/10.3389/fphar.2020.591570