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A matrigel-free method to generate matured human cerebral organoids using 3D-Printed microwell arrays
The current methods of generating human cerebral organoids rely excessively on the use of Matrigel or other external extracellular matrices (ECM) for cell micro-environmental modulation. Matrigel embedding is problematic for long-term culture and clinical applications due to high inconsistency and o...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
KeAi Publishing
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577195/ https://www.ncbi.nlm.nih.gov/pubmed/33134606 http://dx.doi.org/10.1016/j.bioactmat.2020.10.003 |