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Ares-GT: Design of guide RNAs targeting multiple genes for CRISPR-Cas experiments
Guide RNA design for CRISPR genome editing of gene families is a challenging task as usually good candidate sgRNAs are tagged with low scores precisely because they match several locations in the genome, thus time-consuming manual evaluation of targets is required. To address this issues, I have dev...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Public Library of Science
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577430/ https://www.ncbi.nlm.nih.gov/pubmed/33085710 http://dx.doi.org/10.1371/journal.pone.0241001 |