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Ares-GT: Design of guide RNAs targeting multiple genes for CRISPR-Cas experiments

Guide RNA design for CRISPR genome editing of gene families is a challenging task as usually good candidate sgRNAs are tagged with low scores precisely because they match several locations in the genome, thus time-consuming manual evaluation of targets is required. To address this issues, I have dev...

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Detalles Bibliográficos
Autor principal: Minguet, Eugenio Gómez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577430/
https://www.ncbi.nlm.nih.gov/pubmed/33085710
http://dx.doi.org/10.1371/journal.pone.0241001