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Genome-wide transposon mutagenesis of paramyxoviruses reveals constraints on genomic plasticity

The antigenic and genomic stability of paramyxoviruses remains a mystery. Here, we evaluate the genetic plasticity of Sendai virus (SeV) and mumps virus (MuV), sialic acid-using paramyxoviruses that infect mammals from two Paramyxoviridae subfamilies (Orthoparamyxovirinae and Rubulavirinae). We perf...

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Detalles Bibliográficos
Autores principales: Ikegame, Satoshi, Beaty, Shannon M., Stevens, Christian, Won, Taylor, Park, Arnold, Sachs, David, Hong, Patrick, Lee, Benhur, Thibault, Patricia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577504/
https://www.ncbi.nlm.nih.gov/pubmed/33035269
http://dx.doi.org/10.1371/journal.ppat.1008877