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Association of blood-based transcriptional risk scores with biomarkers for Alzheimer disease

OBJECTIVE: To determine whether transcriptional risk scores (TRSs), a summation of polarized expression levels of functional genes, reflect the risk of Alzheimer disease (AD). METHODS: Blood transcriptome data were from Caucasian participants, which included AD, mild cognitive impairment, and cognit...

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Detalles Bibliográficos
Autores principales: Park, Young Ho, Hodges, Angela, Simmons, Andrew, Lovestone, Simon, Weiner, Michael W., Kim, SangYun, Saykin, Andrew J., Nho, Kwangsik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577551/
https://www.ncbi.nlm.nih.gov/pubmed/33134515
http://dx.doi.org/10.1212/NXG.0000000000000517