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Association of blood-based transcriptional risk scores with biomarkers for Alzheimer disease
OBJECTIVE: To determine whether transcriptional risk scores (TRSs), a summation of polarized expression levels of functional genes, reflect the risk of Alzheimer disease (AD). METHODS: Blood transcriptome data were from Caucasian participants, which included AD, mild cognitive impairment, and cognit...
Autores principales: | Park, Young Ho, Hodges, Angela, Simmons, Andrew, Lovestone, Simon, Weiner, Michael W., Kim, SangYun, Saykin, Andrew J., Nho, Kwangsik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577551/ https://www.ncbi.nlm.nih.gov/pubmed/33134515 http://dx.doi.org/10.1212/NXG.0000000000000517 |
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