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Genetic risk for Alzheimer disease predicts hippocampal volume through the human lifespan
OBJECTIVE: To test the hypothesis that genetic risk for Alzheimer disease (AD) may represent a stable influence on the brain from early in life, rather than being primarily age dependent, we investigated in a lifespan sample of 1,181 persons with a total of 2,690 brain scans, whether higher polygeni...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577559/ https://www.ncbi.nlm.nih.gov/pubmed/33134508 http://dx.doi.org/10.1212/NXG.0000000000000506 |