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Genetic risk for Alzheimer disease predicts hippocampal volume through the human lifespan

OBJECTIVE: To test the hypothesis that genetic risk for Alzheimer disease (AD) may represent a stable influence on the brain from early in life, rather than being primarily age dependent, we investigated in a lifespan sample of 1,181 persons with a total of 2,690 brain scans, whether higher polygeni...

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Detalles Bibliográficos
Autores principales:	Walhovd, Kristine B., Fjell, Anders M., Sørensen, Øystein, Mowinckel, Athanasia Monika, Reinbold, Céline Sonja, Idland, Ane-Victoria, Watne, Leiv Otto, Franke, Andre, Dobricic, Valerija, Kilpert, Fabian, Bertram, Lars, Wang, Yunpeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577559/ https://www.ncbi.nlm.nih.gov/pubmed/33134508 http://dx.doi.org/10.1212/NXG.0000000000000506

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