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MCART1/SLC25A51 is required for mitochondrial NAD transport

The nicotinamide adenine dinucleotide (NAD(+)/NADH) pair is a cofactor in redox reactions and is particularly critical in mitochondria as it connects substrate oxidation by the tricarboxylic acid (TCA) cycle to adenosine triphosphate generation by the electron transport chain (ETC) and oxidative pho...

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Detalles Bibliográficos
Autores principales: Kory, Nora, uit de Bos, Jelmi, van der Rijt, Sanne, Jankovic, Nevena, Güra, Miriam, Arp, Nicholas, Pena, Izabella A., Prakash, Gyan, Chan, Sze Ham, Kunchok, Tenzin, Lewis, Caroline A., Sabatini, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577609/
https://www.ncbi.nlm.nih.gov/pubmed/33087354
http://dx.doi.org/10.1126/sciadv.abe5310