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Three-Dimensional Human Alveolar Stem Cell Culture Models Reveal Infection Response to SARS-CoV-2

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is the cause of a present pandemic, infects human lung alveolar type 2 (hAT2) cells. Characterizing pathogenesis is crucial for developing vaccines and therapeutics. However, the lack of models mirroring the cellular physiology and...

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Detalles Bibliográficos
Autores principales: Youk, Jeonghwan, Kim, Taewoo, Evans, Kelly V., Jeong, Young-Il, Hur, Yongsuk, Hong, Seon Pyo, Kim, Je Hyoung, Yi, Kijong, Kim, Su Yeon, Na, Kwon Joong, Bleazard, Thomas, Kim, Ho Min, Fellows, Mick, Mahbubani, Krishnaa T., Saeb-Parsy, Kourosh, Kim, Seon Young, Kim, Young Tae, Koh, Gou Young, Choi, Byeong-Sun, Ju, Young Seok, Lee, Joo-Hyeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577700/
https://www.ncbi.nlm.nih.gov/pubmed/33142113
http://dx.doi.org/10.1016/j.stem.2020.10.004