Integrated proteomics reveals brain-based cerebrospinal fluid biomarkers in asymptomatic and symptomatic Alzheimer’s disease

Alzheimer’s disease (AD) lacks protein biomarkers reflective of its diverse underlying pathophysiology, hindering diagnostic and therapeutic advancements. Here, we used integrative proteomics to identify cerebrospinal fluid (CSF) biomarkers representing a wide spectrum of AD pathophysiology. Multipl...

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Detalles Bibliográficos
Autores principales: Higginbotham, Lenora, Ping, Lingyan, Dammer, Eric B., Duong, Duc M., Zhou, Maotian, Gearing, Marla, Hurst, Cheyenne, Glass, Jonathan D., Factor, Stewart A., Johnson, Erik C. B., Hajjar, Ihab, Lah, James J., Levey, Allan I., Seyfried, Nicholas T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577712/
https://www.ncbi.nlm.nih.gov/pubmed/33087358
http://dx.doi.org/10.1126/sciadv.aaz9360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577712/
https://www.ncbi.nlm.nih.gov/pubmed/33087358
http://dx.doi.org/10.1126/sciadv.aaz9360

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