Endogenous retroviruses drive KRAB zinc-finger protein family expression for tumor suppression

Gene expression aberration is a hallmark of cancers, but the mechanisms underlying such aberrations remain unclear. Human endogenous retroviruses (HERVs) are genomic repetitive elements that potentially function as enhancers. Since numerous HERVs are epigenetically activated in tumors, their activat...

Descripción completa

Detalles Bibliográficos
Autores principales: Ito, Jumpei, Kimura, Izumi, Soper, Andrew, Coudray, Alexandre, Koyanagi, Yoshio, Nakaoka, Hirofumi, Inoue, Ituro, Turelli, Priscilla, Trono, Didier, Sato, Kei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577720/
https://www.ncbi.nlm.nih.gov/pubmed/33087347
http://dx.doi.org/10.1126/sciadv.abc3020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577720/
https://www.ncbi.nlm.nih.gov/pubmed/33087347
http://dx.doi.org/10.1126/sciadv.abc3020

Ejemplares similares