Cargando…

Endogenous retroviruses drive KRAB zinc-finger protein family expression for tumor suppression

Gene expression aberration is a hallmark of cancers, but the mechanisms underlying such aberrations remain unclear. Human endogenous retroviruses (HERVs) are genomic repetitive elements that potentially function as enhancers. Since numerous HERVs are epigenetically activated in tumors, their activat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ito, Jumpei, Kimura, Izumi, Soper, Andrew, Coudray, Alexandre, Koyanagi, Yoshio, Nakaoka, Hirofumi, Inoue, Ituro, Turelli, Priscilla, Trono, Didier, Sato, Kei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577720/ https://www.ncbi.nlm.nih.gov/pubmed/33087347 http://dx.doi.org/10.1126/sciadv.abc3020

Ejemplares similares

KRAB zinc finger protein ZNF676 controls the transcriptional influence of LTR12-related endogenous retrovirus sequences
por: Iouranova, Alexandra, et al.
Publicado: (2022)

Genetic features and genomic targets of human KRAB-zinc finger proteins
por: de Tribolet-Hardy, Jonas, et al.
Publicado: (2023)

Primate-restricted KRAB zinc finger proteins and target retrotransposons control gene expression in human neurons
por: Turelli, Priscilla, et al.
Publicado: (2020)

The interactome of KRAB zinc finger proteins reveals the evolutionary history of their functional diversification
por: Helleboid, Pierre‐Yves, et al.
Publicado: (2019)

The KRAB zinc finger protein ZFP809 is required to initiate epigenetic silencing of endogenous retroviruses
por: Wolf, Gernot, et al.
Publicado: (2015)

KRAB-zinc-finger proteins regulate endogenous retroviruses to sculpt germline transcriptomes and genome evolution
por: Otsuka, Kai, et al.
Publicado: (2023)

Systematic identification and characterization of regulatory elements derived from human endogenous retroviruses
por: Ito, Jumpei, et al.
Publicado: (2017)

Zinc Fingers Function Cooperatively with KRAB Domain for Nuclear Localization of KRAB-Containing Zinc Finger Proteins
por: Wang, Wei, et al.
Publicado: (2014)

KRAB-zinc finger protein gene expansion in response to active retrotransposons in the murine lineage
por: Wolf, Gernot, et al.
Publicado: (2020)

The mouse genome displays highly dynamic populations of KRAB-zinc finger protein genes and related genetic units
por: Kauzlaric, Annamaria, et al.
Publicado: (2017)

KRAB-containing zinc-finger repressor proteins
por: Urrutia, Raul
Publicado: (2003)

KRAB–Zinc Finger Proteins and KAP1 Can Mediate Long-Range Transcriptional Repression through Heterochromatin Spreading
por: Groner, Anna C., et al.
Publicado: (2010)

TRIM28 Represses Transcription of Endogenous Retroviruses in Neural Progenitor Cells
por: Fasching, Liana, et al.
Publicado: (2014)

Evolving imprinting control regions: KRAB zinc fingers hold the key
por: Juan, Aimee M., et al.
Publicado: (2019)

KRAB zinc finger protein diversification drives mammalian interindividual methylation variability
por: Bertozzi, Tessa M., et al.
Publicado: (2020)

Mapping the interaction between Trim28 and the KRAB domain at the center of Trim28 silencing of endogenous retroviruses
por: Taka, Jamie R. H., et al.
Publicado: (2022)

KRAB-Zinc Finger Proteins: A Repressor Family Displaying Multiple Biological Functions
por: Lupo, Angelo, et al.
Publicado: (2013)

Downregulation of KRAB zinc finger proteins in 5-fluorouracil resistant colorectal cancer cells
por: Chauvin, Anaïs, et al.
Publicado: (2022)

Structural Evolution of Gene Promoters Driven by Primate-Specific KRAB Zinc Finger Proteins
por: Farmiloe, Grace, et al.
Publicado: (2023)

Quantifying the arms race between LINE-1 and KRAB-zinc finger genes through TECookbook
por: Zuo, Zheng
Publicado: (2023)

The Transcriptional Repressive Activity of KRAB Zinc Finger Proteins Does Not Correlate with Their Ability to Recruit TRIM28
por: Murphy, Kristin E., et al.
Publicado: (2016)

The KRAB-zinc-finger protein ZFP708 mediates epigenetic repression at RMER19B retrotransposons
por: Seah, Michelle K. Y., et al.
Publicado: (2019)

Mutant KRAS regulates transposable element RNA and innate immunity via KRAB zinc-finger genes
por: Reggiardo, Roman E., et al.
Publicado: (2022)

Species-specific KRAB-ZFPs function as repressors of retroviruses by targeting PBS regions
por: Yang, Bo, et al.
Publicado: (2022)

ES cell potency fluctuates with endogenous retrovirus activity
por: Macfarlan, Todd S., et al.
Publicado: (2012)

An evolutionary arms race between KRAB zinc finger genes 91/93 and SVA/L1 retrotransposons
por: Jacobs, Frank MJ, et al.
Publicado: (2014)

Myocardial ischemic preconditioning upregulated protein 1(Mipu1):zinc finger protein 667 - a multifunctional KRAB/C(2)H(2) zinc finger protein
por: Han, D., et al.
Publicado: (2014)

The KRAB Zinc Finger Protein Roma/Zfp157 Is a Critical Regulator of Cell-Cycle Progression and Genomic Stability
por: Ho, Teresa L.F., et al.
Publicado: (2016)

KRAB-type zinc-finger proteins PITA and PISA specifically regulate p53-dependent glycolysis and mitochondrial respiration
por: Wang, Shan, et al.
Publicado: (2018)

Role of the Transcriptional Repressor Zinc Finger with KRAB and SCAN Domains 3 (ZKSCAN3) in Retinal Pigment Epithelial Cells
por: Pan, Hsuan-Yeh, et al.
Publicado: (2021)

The diversity of zinc-finger genes on human chromosome 19 provides an evolutionary mechanism for defense against inherited endogenous retroviruses
por: Lukic, S, et al.
Publicado: (2014)

Hominoid-Specific Transposable Elements and KZFPs Facilitate Human Embryonic Genome Activation and Control Transcription in Naive Human ESCs
por: Pontis, Julien, et al.
Publicado: (2019)

Interplay of TRIM28 and DNA methylation in controlling human endogenous retroelements
por: Turelli, Priscilla, et al.
Publicado: (2014)

Movements of Ancient Human Endogenous Retroviruses Detected in SOX2-Expressing Cells
por: Monde, Kazuaki, et al.
Publicado: (2022)

MAGE I Transcription Factors Regulate KAP1 and KRAB Domain Zinc Finger Transcription Factor Mediated Gene Repression
por: Xiao, Tony Z., et al.
Publicado: (2011)

The role of ZFP57 and additional KRAB-zinc finger proteins in the maintenance of human imprinted methylation and multi-locus imprinting disturbances
por: Monteagudo-Sánchez, Ana, et al.
Publicado: (2020)

Conserved paradoxical relationships among the evolutionary, structural and expressional features of KRAB zinc-finger proteins reveal their special functional characteristics
por: Shen, Pan, et al.
Publicado: (2021)

Cytotoxic Effects during Knock Out of Multiple Porcine Endogenous Retrovirus (PERV) Sequences in the Pig Genome by Zinc Finger Nucleases (ZFN)
por: Semaan, Marwan, et al.
Publicado: (2015)

Type I Interferon Responses by HIV-1 Infection: Association with Disease Progression and Control
por: Soper, Andrew, et al.
Publicado: (2018)

Comparison of ChIP-Seq Data and a Reference Motif Set for Human KRAB C2H2 Zinc Finger Proteins
por: Barazandeh, Marjan, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_6gk0ksjvsepkpo3pile8o2ijv0