Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon–anticodon pairing

Modifications in the tRNA anticodon loop, adjacent to the three-nucleotide anticodon, influence translation fidelity by stabilizing the tRNA to allow for accurate reading of the mRNA genetic code. One example is the N1-methylguanosine modification at guanine nucleotide 37 (m(1)G37) located in the an...

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Detalles Bibliográficos
Autores principales: Hoffer, Eric D, Hong, Samuel, Sunita, S, Maehigashi, Tatsuya, Gonzalez, Ruben L, Whitford, Paul C, Dunham, Christine M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577736/
https://www.ncbi.nlm.nih.gov/pubmed/33016876
http://dx.doi.org/10.7554/eLife.51898

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577736/
https://www.ncbi.nlm.nih.gov/pubmed/33016876
http://dx.doi.org/10.7554/eLife.51898

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