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Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon–anticodon pairing
Modifications in the tRNA anticodon loop, adjacent to the three-nucleotide anticodon, influence translation fidelity by stabilizing the tRNA to allow for accurate reading of the mRNA genetic code. One example is the N1-methylguanosine modification at guanine nucleotide 37 (m(1)G37) located in the an...
Autores principales: | Hoffer, Eric D, Hong, Samuel, Sunita, S, Maehigashi, Tatsuya, Gonzalez, Ruben L, Whitford, Paul C, Dunham, Christine M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577736/ https://www.ncbi.nlm.nih.gov/pubmed/33016876 http://dx.doi.org/10.7554/eLife.51898 |
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