Light-regulated allosteric switch enables temporal and subcellular control of enzyme activity

Engineered allosteric regulation of protein activity provides significant advantages for the development of robust and broadly applicable tools. However, the application of allosteric switches in optogenetics has been scarce and suffers from critical limitations. Here, we report an optogenetic appro...

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Detalles Bibliográficos
Autores principales: Shaaya, Mark, Fauser, Jordan, Zhurikhina, Anastasia, Conage-Pough, Jason E, Huyot, Vincent, Brennan, Martin, Flower, Cameron T, Matsche, Jacob, Khan, Shahzeb, Natarajan, Viswanathan, Rehman, Jalees, Kota, Pradeep, White, Forest M, Tsygankov, Denis, Karginov, Andrei V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577742/
https://www.ncbi.nlm.nih.gov/pubmed/32965214
http://dx.doi.org/10.7554/eLife.60647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577742/
https://www.ncbi.nlm.nih.gov/pubmed/32965214
http://dx.doi.org/10.7554/eLife.60647

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