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rG4-seeker enables high-confidence identification of novel and non-canonical rG4 motifs from rG4-seq experiments
We recently developed the rG4-seq method to detect and map in vitro RNA G-quadruplex (rG4s) structures on a transcriptome-wide scale. rG4-seq of purified human HeLa RNA has revealed many non-canonical rG4s and the effects adjacent sequences have on rG4 formation. In this study, we aimed to improve t...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577744/ https://www.ncbi.nlm.nih.gov/pubmed/32338139 http://dx.doi.org/10.1080/15476286.2020.1740470 |