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rG4-seeker enables high-confidence identification of novel and non-canonical rG4 motifs from rG4-seq experiments

We recently developed the rG4-seq method to detect and map in vitro RNA G-quadruplex (rG4s) structures on a transcriptome-wide scale. rG4-seq of purified human HeLa RNA has revealed many non-canonical rG4s and the effects adjacent sequences have on rG4 formation. In this study, we aimed to improve t...

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Detalles Bibliográficos
Autores principales: Chow, Eugene Yui-Ching, Lyu, Kaixin, Kwok, Chun Kit, Chan, Ting-Fung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577744/
https://www.ncbi.nlm.nih.gov/pubmed/32338139
http://dx.doi.org/10.1080/15476286.2020.1740470