An accelerated surface-mediated stress assay of antibody instability for developability studies

High physical stability is required for the development of monoclonal antibodies (mAbs) into successful therapeutic products. Developability assays are used to predict physical stability issues such as high viscosity and poor conformational stability, but protein aggregation remains a challenging pr...

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Detalles Bibliográficos
Autores principales: Kopp, Marie R.G., Wolf Pérez, Adriana-Michelle, Zucca, Marta Virginia, Capasso Palmiero, Umberto, Friedrichsen, Brigitte, Lorenzen, Nikolai, Arosio, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577746/
https://www.ncbi.nlm.nih.gov/pubmed/32954930
http://dx.doi.org/10.1080/19420862.2020.1815995

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577746/
https://www.ncbi.nlm.nih.gov/pubmed/32954930
http://dx.doi.org/10.1080/19420862.2020.1815995

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