Cargando…

A psychiatric disease-related circular RNA controls synaptic gene expression and cognition

Although circular RNAs (circRNAs) are enriched in the mammalian brain, very little is known about their potential involvement in brain function and psychiatric disease. Here, we show that circHomer1a, a neuronal-enriched circRNA abundantly expressed in the frontal cortex, derived from Homer protein...

Descripción completa

Detalles Bibliográficos
Autores principales: Zimmerman, Amber J., Hafez, Alexander K., Amoah, Stephen K., Rodriguez, Brian A., Dell’Orco, Michela, Lozano, Evelyn, Hartley, Brigham J., Alural, Begüm, Lalonde, Jasmin, Chander, Praveen, Webster, Maree J., Perlis, Roy H., Brennand, Kristen J., Haggarty, Stephen J., Weick, Jason, Perrone-Bizzozero, Nora, Brigman, Jonathan L., Mellios, Nikolaos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577899/
https://www.ncbi.nlm.nih.gov/pubmed/31988434
http://dx.doi.org/10.1038/s41380-020-0653-4