Pianp deficiency links GABA(B) receptor signaling and hippocampal and cerebellar neuronal cell composition to autism-like behavior

Pianp (also known as Leda-1) is a type I transmembrane protein with preferential expression in the mammalian CNS. Its processing is characterized by proteolytic cleavage by a range of proteases including Adam10, Adam17, MMPs, and the γ-secretase complex. Pianp can interact with Pilrα and the GB1a su...

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Detalles Bibliográficos
Autores principales: Winkler, Manuel, Biswas, Siladitta, Berger, Stefan M., Küchler, Moritz, Preisendörfer, Laurens, Choo, Myeongjeong, Früh, Simon, Rem, Pascal D., Enkel, Thomas, Arnold, Bernd, Komljenovic, Dorde, Sticht, Carsten, Goerdt, Sergij, Bettler, Bernhard, von Bohlen und Halbach, Oliver, Bartsch, Dusan, Géraud, Cyrill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577901/
https://www.ncbi.nlm.nih.gov/pubmed/31511635
http://dx.doi.org/10.1038/s41380-019-0519-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577901/
https://www.ncbi.nlm.nih.gov/pubmed/31511635
http://dx.doi.org/10.1038/s41380-019-0519-9

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