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Plant isoquinoline alkaloids as potential neurodrugs: A comparative study of the effects of benzo[c]phenanthridine and berberine-based compounds on β-amyloid aggregation

Herein we present a comparative study of the effects of isoquinoline alkaloids belonging to benzo[c]phenanthridine and berberine families on β-amyloid aggregation. Results obtained using a Thioflavine T (ThT) fluorescence assay and circular dichroism (CD) spectroscopy suggested that the benzo[c]phen...

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Detalles Bibliográficos
Autores principales: Marasco, Daniela, Vicidomini, Caterina, Krupa, Pawel, Cioffi, Federica, Huy, Pham Dinh Quoc, Li, Mai Suan, Florio, Daniele, Broersen, Kerensa, De Pandis, Maria Francesca, Roviello, Giovanni N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577920/
https://www.ncbi.nlm.nih.gov/pubmed/33098838
http://dx.doi.org/10.1016/j.cbi.2020.109300