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Inhibiting the two-component system GraXRS with verteporfin to combat Staphylococcus aureus infections

Infections caused by Staphylococcus aureus pose a serious and sometimes fatal health issue. With the aim of exploring a novel therapeutic approach, we chose GraXRS, a Two-Component System (TCS) that determines bacterial resilience against host innate immune barriers, as an alternative target to disa...

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Detalles Bibliográficos
Autores principales: Prieto, Juana María, Rapún-Araiz, Beatriz, Gil, Carmen, Penadés, José R., Lasa, Iñigo, Latasa, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577973/
https://www.ncbi.nlm.nih.gov/pubmed/33087792
http://dx.doi.org/10.1038/s41598-020-74873-5