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Testis-specific peroxiredoxin 4 variant is not absolutely required for spermatogenesis and fertility in mice

PRDX4, a member of peroxiredoxin family, is largely concentrated in the endoplasmic reticulum (ER) and plays a pivotal role in the redox relay during oxidative protein folding as well as in peroxidase reactions. A testis-specific PRDX4 variant transcript (PRDX4t) lacks the conventional exon 1, which...

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Detalles Bibliográficos
Autores principales: Homma, Takujiro, Kurahashi, Toshihiro, Ishii, Naoki, Shirasawa, Nobuyuki, Fujii, Junichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577974/
https://www.ncbi.nlm.nih.gov/pubmed/33087733
http://dx.doi.org/10.1038/s41598-020-74667-9