Sensitivity enhancement of homonuclear multidimensional NMR correlations for labile sites in proteins, polysaccharides, and nucleic acids

Multidimensional TOCSY and NOESY are central experiments in chemical and biophysical NMR. Limited efficiencies are an intrinsic downside of these methods, particularly when targeting labile sites. This study demonstrates that the decoherence imparted on these protons through solvent exchanges can, w...

Descripción completa

Detalles Bibliográficos
Autores principales: Novakovic, Mihajlo, Kupče, Ēriks, Oxenfarth, Andreas, Battistel, Marcos D., Freedberg, Darón I., Schwalbe, Harald, Frydman, Lucio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577996/
https://www.ncbi.nlm.nih.gov/pubmed/33087707
http://dx.doi.org/10.1038/s41467-020-19108-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577996/
https://www.ncbi.nlm.nih.gov/pubmed/33087707
http://dx.doi.org/10.1038/s41467-020-19108-x

Ejemplares similares