Impaired autophagy increases susceptibility to endotoxin-induced chronic pancreatitis

Chronic pancreatitis (CP) is associated with elevated plasma levels of bacterial lipopolysaccharide (LPS) and we have demonstrated reduced acinar cell autophagy in human CP tissue. Therefore, we investigated the role of autophagy in experimental endotoxin-induced pancreatic injury and aimed to ident...

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Detalles Bibliográficos
Autores principales: Xia, L., Xu, Z., Zhou, X., Bergmann, F., Grabe, N., Büchler, M. W., Neoptolemos, J. P., Hackert, T., Kroemer, G., Fortunato, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578033/
https://www.ncbi.nlm.nih.gov/pubmed/33087696
http://dx.doi.org/10.1038/s41419-020-03050-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578033/
https://www.ncbi.nlm.nih.gov/pubmed/33087696
http://dx.doi.org/10.1038/s41419-020-03050-3

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