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Impaired autophagy increases susceptibility to endotoxin-induced chronic pancreatitis
Chronic pancreatitis (CP) is associated with elevated plasma levels of bacterial lipopolysaccharide (LPS) and we have demonstrated reduced acinar cell autophagy in human CP tissue. Therefore, we investigated the role of autophagy in experimental endotoxin-induced pancreatic injury and aimed to ident...
Autores principales: | Xia, L., Xu, Z., Zhou, X., Bergmann, F., Grabe, N., Büchler, M. W., Neoptolemos, J. P., Hackert, T., Kroemer, G., Fortunato, F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578033/ https://www.ncbi.nlm.nih.gov/pubmed/33087696 http://dx.doi.org/10.1038/s41419-020-03050-3 |
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