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Targeting Orai1-Mediated Store-Operated Ca(2+) Entry in Heart Failure
The archetypal store-operated Ca(2+) channels (SOCs), Orai1, which are stimulated by the endo/sarcoplasmic reticulum (ER/SR) Ca(2+) sensor stromal interaction molecule 1 (STIM1) upon Ca(2+) store depletion is traditionally viewed as instrumental for the function of non-excitable cells. In the recent...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578222/ https://www.ncbi.nlm.nih.gov/pubmed/33117812 http://dx.doi.org/10.3389/fcell.2020.586109 |