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Targeting Orai1-Mediated Store-Operated Ca(2+) Entry in Heart Failure

The archetypal store-operated Ca(2+) channels (SOCs), Orai1, which are stimulated by the endo/sarcoplasmic reticulum (ER/SR) Ca(2+) sensor stromal interaction molecule 1 (STIM1) upon Ca(2+) store depletion is traditionally viewed as instrumental for the function of non-excitable cells. In the recent...

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Detalles Bibliográficos
Autores principales: Luo, Rui, Gomez, Ana-Maria, Benitah, Jean-Pierre, Sabourin, Jessica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578222/
https://www.ncbi.nlm.nih.gov/pubmed/33117812
http://dx.doi.org/10.3389/fcell.2020.586109